Medical Device
Manufacturer

Medical Aesthetics·Hyaluronic acid

GANA HA

Monophasic cross-linked hyaluronic acid with a 10 % cross-linking ratio and small, uniform particles: three filler types for different injection depths, plus a Booster type for mesotherapy.

01 At a glance

Hyaluronic acid dermal filler — Types A, B, C and Booster

  • Presentation1.2 ml prefilled syringe × 1 per box (Types A, B and C); Booster type 2.5 ml
  • Composition
    • Cross-linked hyaluronic acid (BDDE cross-linked), no non-cross-linked HA added
    • HA concentration: Type A 24 mg/cc · Type B 22 mg/cc · Type C 20 mg/cc · Booster 6 mg/cc
    • Cross-linking ratio 10 % (Booster 5 %)
  • ChemistryHyaluronic acid
  • Registrations3 active · South Korea · Russia
  • Catalogue2026 GANA R&D product catalogue, p. 10–11
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GANA HA — Type A, B and C cartons with a 1.2 ml prefilled syringe

02 On the record

Registrations for this product

GANA R&D is named as manufacturer on each entry. Every number can be checked on the authority’s public register.

Name as registeredJurisdictionRegistrationGrantedScopeVerify
GANA HA — Umbrella licence covering ART AQUA and 21 further products South Korea · MFDS 제허15-1662 10 Dec 2015 Export Public register→
GANA HA TYPE South Korea · MFDS 제허23-128 24 Feb 2023 Export Public register→
GANA HA (A/B/C) Russia · Roszdravnadzor РЗН 2021/14277 7 May 2021 — Public register→

Roszdravnadzor’s registry uses a Russian state certificate. Browsers outside Russia may show a security warning before the record opens.

Manufacturer

  • MFDS manufacturing licenceGANA R&D Co., Ltd. · MFDS No. 4490 · Public register→
  • GMP certificateKCL-ABBA-19926 · valid to 3 Mar 2027
  • Manufacturing site555 Dunchon-daero, Jungwon-gu, Seongnam-si 13215, Republic of Korea

03 From the catalogue

Product details

Reproduced from the 2026 GANA R&D product catalogue. For healthcare professionals; these notes do not replace the instructions for use supplied with the product.

Characteristics of GANA HA

  1. No addition of non-cross-linked HA
  2. Highest cross-linking ratio
  3. Highest HA concentration
  4. Small particle size, so the shape is easy to mould
  5. Higher viscosity than other dermal fillers
  6. Longest duration
  7. Low extrusion force
Biphasic and monophasic HA fillers
Biphasic HA fillersMonophasic HA fillers
Non-cross-linked HAAdded — disappears in 1–2 weeksNot added
Particle sizeLarge—
DurationRelatively shortLonger
Cross-linking ratioLowRelatively high
ShapingEasy to mouldDifficult to mould

GANA HA compared with existing fillers

MonophasicBiphasicGANA HA
Cross-linking ratio6–8 %2–4 %10 %
HA concentration (mg/cc)20–2420–2420–24
Cross-linking agentBDDEBDDEBDDE
Duration (months)6–126–1812–18
Particle sizeNone100–2000 µm50–100 µm
Viscosity (cPs)2–4 × 10⁶1–4 × 10⁶4–7 × 10⁶

Types and recommended use

TypeVolumeInjection layerNeedleHA (mg/cc)Cross-linkingRecommended use
Type A1.2 mlSubcutaneous25 G2410 %Large-volume augmentation
Type B1.2 mlDeep dermis27 G2210 %Moderate wrinkles
Type C1.2 mlDermis30 G2010 %Fine wrinkles
Booster2.5 mlEpidermis30 G65 %Mesotherapy
  • Forehead — Type A, Booster type
  • Around the eyes — Type C, Booster type
  • Nose — Type A, Booster type
  • Nasolabial fold — Type B, Booster type
  • Lips — Type B
  • Chin — Type A, Booster type

Specification

Test itemStandardResult
AppearanceColourless, transparent; no visible foreign matter, no air bubblesQualified
Hyaluronate content24 / 22 / 20 mg/mlQualified
pH6.5–7.6Qualified
Osmotic pressure (mOsmol/L)0.9–1.1Qualified
Particle size distributionType A: 1 mm, 23 G · Type B: 200–500 µm, 27 G · Type C: 50–100 µm, 30 G · Booster: under 30 µmQualified
Cross-linking agent (BDDE) residue≤ 2.0 µg/gQualified
Protein≤ 1.0 %Qualified
Heavy metals≤ 20 ppmQualified
Bacteria testNo bacterial growthQualified
Bacterial endotoxin test≤ 0.5 EU/mLQualified
Viscosity4–6 × 10⁶ cPsQualified
HaemolysisNo haemolysis ringQualified

The products were tested in conformity with the GANA R&D standard.

Recommended dose

  • Nose: 1–2 ml
  • Nasolabial fold: 2–3 ml
  • Forehead: 3–5 ml
  • Lips: over 1 ml each side
  • Cheek: 4–10 ml
  • Short chin: 2–4 ml
  • Sunken eye: 1 ml
  • Temporal depression: over 2 ml each side

04 Portfolio

Other dermal fillers from GANA R&D

All dermal fillers→

Ask for the dossier.

Registration certificates, instructions for use and technical documents for this product are available to distributors and clinics on request.

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